Exosome Application in Bursa
What are exosomes?
Exosomes are tiny vesicles, too small to be seen with the eye, that cells release outward and that carry proteins, lipids and fragments of genetic material (extracellular vesicles). They are known to play a role in communication between cells. In recent years, the possible effects of these vesicles on skin renewal have been under investigation, and exosome-containing products are used in skin care.
The source of products on the market varies: there are exosome-containing products obtained from plant cells, from cell cultures produced in the laboratory, or from other sources. The content, purity and legal classification of the products differ from one another, and regulations in this area vary from country to country. At our practice, the content, source and legal status of the product to be used are shared with the person before the application.
What does the scientific evidence say?
Most studies on exosomes are laboratory and animal studies or early-stage clinical studies conducted with a small number of people. Although there are publications reporting favorable changes in skin texture, hydration and fine lines, long-term results and comparisons of different products are not yet sufficient. For this reason, exosome application is described as a supportive care application aimed at skin quality, with expectations kept realistic.
Who is it suitable for, and who should not have it?
It may be considered for adults in good general health with skin quality complaints such as dullness, fine lines, visible pores, mild acne marks or sun-related wear. There are also protocols applied to the scalp for hair thinning; the cause of hair loss is investigated first. The application is not performed, or is postponed, in the following situations:
- Pregnancy and breastfeeding,
- Active infection, cold sores, an open wound or inflamed acne in the treatment area,
- Active cancer or a recently completed cancer process,
- Known allergy to the product's ingredients,
- A bleeding disorder, uncontrolled diabetes or uncontrolled autoimmune disease,
- Use of isotretinoin (an acne medication) within the last 6 months and a marked tendency to keloids (because of microneedling).
In people using blood thinners, the tendency to bruise and bleed may increase; tell the physician about the medications you use, and do not stop any medication on your own.
How is it done?
First, skin type, complaints and medical history are evaluated. The skin is cleansed and, if needed, a numbing cream is applied for 20–30 minutes. Then very fine, controlled channels are opened in the skin with a microneedling device, and the exosome-containing product is spread over the skin surface. In some protocols, the product is used after another procedure such as fractional laser. Including preparation, the procedure usually takes 45–60 minutes.
The number of sessions varies with the person and the protocol used; usually 3–4 sessions are planned at 3–4 week intervals. The plan is made together at the first evaluation.
When does the effect begin, and how long does it last?
In the first days after the procedure, a temporary feeling of freshness in the skin may be described; however, the change in skin quality is gradual and is usually evaluated a few weeks after the sessions are completed. The effect is temporary and varies markedly from person to person; age, skin structure, sun protection and habits such as smoking affect the result. In some people the difference may remain limited. Periodic maintenance sessions may be recommended to sustain it.
Possible side effects
The most common are redness, sensitivity, mild swelling and a feeling of warmth; these usually subside within 1–3 days. Mild flaking and dryness may occur for a few days. Less often, acne flare-ups, infection, an allergic reaction or, especially in darker skin, temporary color change may be seen. If you notice increasing pain, discharge or fever in the microneedled area, contact the practice.
Aftercare
- Do not wear makeup for the first 24 hours; cleanse the skin only with the gentle products the physician recommends.
- Avoid saunas, Turkish baths, swimming pools and intense exercise for 48 hours.
- Use sunscreen; avoid strong sun for one week.
- For one week, pause irritating products such as retinoids and acid peels.
- If flaking occurs, do not pick at it.
Exosome application in Bursa
At our private practice in Nilüfer, exosome application is planned after a skin evaluation and information about the product; expectations are kept realistic. For other options aimed at skin quality, you can see the mesotherapy, lifting injections and gold needle pages, and for skin texture and the appearance of scars, the fractional laser page.
Treatments are performed by a physician holding a medical aesthetics certificate approved by the Turkish Ministry of Health. Op. Dr. Hakan Sağer is an Obstetrician & Gynecologist.
This content is for information purposes only; a physician's examination is required for diagnosis and treatment.
Frequently asked questions
What are exosomes?
Exosomes are very small vesicles secreted by cells that carry proteins, lipids and fragments of genetic material. They play a role in communication between cells. In skin care, exosome-containing products are usually applied to the skin surface after microneedling; this is not a medicine.
Has the effect of exosome application been proven?
Most studies in this area are laboratory studies and early-stage clinical studies with a small number of people. There are publications reporting favorable changes in skin texture, but long-term data are limited. For this reason, expectations are discussed realistically at the examination.
How many exosome sessions are needed?
Usually 3–4 sessions are planned at 3–4 week intervals; the number varies with skin condition and the protocol used. After the program, periodic maintenance sessions may be recommended.
Does exosome application leave marks?
After microneedling, redness, sensitivity and mild flaking are expected for 1–3 days. Lasting marks are uncommon; to reduce the risk of infection and color change, aftercare advice should be followed and sunscreen should be used.
Can exosomes be applied during pregnancy or breastfeeding?
No. Because there are not enough data on the safety of these products during pregnancy and breastfeeding, the application is not performed; it is re-evaluated after this period ends.
Are exosomes also used for hair?
There are protocols applied to the scalp for hair thinning; however, the evidence is limited. Causes of hair loss such as iron deficiency, thyroid problems or hormonal disorders are investigated first.
What is the fee for exosome application?
The fee depends on the area to be treated, the product to be used and the session plan determined at the examination. For this reason, no figures are given on the website; the fee is determined after the examination. For information, you can call 0 (539) 463 09 72 or send a message on WhatsApp.
Where in Bursa is exosome application performed?
Exosome evaluation and application take place in the procedure room of Op. Dr. Hakan Sağer's private practice in the İhsaniye neighborhood of Nilüfer (Bulvar 224). Consultation hours are Monday–Saturday 08:00–19:30; to book an appointment, you can call 0 (539) 463 09 72.
Op. Dr. Hakan Sağer is an Obstetrician & Gynecologist. He completed his specialty training at the University of Health Sciences (SBÜ) Bursa Yüksek İhtisas Training and Research Hospital; since 2024 he has been seeing patients for pregnancy follow-up, gynecological conditions and aesthetic gynecology at his private practice in Nilüfer, Bursa. The articles on this website are for informational purposes.
This website is for information only and is not advertising. Its content does not replace an examination by a physician. The information on this page is not personal medical advice; the decision on any procedure is made together with the doctor after an examination.